Application
C15 Ceramide-d7 (d18:1-d7/15:0) has been used as a standard to measure C32–C34 ceramides in zebrafish brain and human embryonic kidney cell line (HEK293) by thermo q-exactive plus quadrupole-orbitrap mass spectrometery. It has also been used to measure the concentration of sphingolipids in right submandibular glands of mice by ultra-high-performance liquid chromatography-tandem mass spectrometry (UHPLC/MS/MS).
Biochem/physiol Actions
Ceramides serve as precursors for several sphingolipids. Ceramides play a significant role in cell differentiation, proliferation, and apoptosis. In addition, they also acts as secondary transmitters in cell signaling.
General description
C15 Ceramide (d18:1/15:0) is a synthetic ceramide containing sphingosine with pentadecanoic acid. C15 Ceramide-d7 (d18:1-d7/15:0) is a deuterated derivative of C15 Ceramide (d18:1/15:0).
Packaging
5 mL Amber Glass Screw Cap Vial (860681P-1mg)
This product has met the following criteria to qualify for the following awards: