Application

18:1-d7 Lyso PE (1-oleoyl(d7)-2-hydroxy-sn-glycero-3-phosphoethanolamine) has been used as a component of extraction solvent for lipid isolation from biological samples. It has also been used as an isotopically labeled lipid internal standard for correction of lipids detected in lipid droplets using shotgun mass spectrometry analysis.

Biochem/physiol Actions

Lysophosphatidylethanolamine (LPE) plays a key role in neuronal differentiation in PC12 cells. It possesses antibacterial and antifungal activity. LPE also favour the calcium transport through G-protein-coupled receptor (GPCR).

General description

18:1-d7 Lyso PE (1-oleoyl(d7)-2-hydroxy-sn-glycero-3-phosphoethanolamine) is a deuterated phospholipid. The glycerol is esterified with oleic acid. Oleic acid harbors the deuterium ions. Lysophosphatidylethanolamine (LPE) is generated from phosphatidylethanolamine by the action of enzyme phospholipase A2.

This deuterium labeled lipid is also available in a formulation of multiple lipid standards. The SPLASH^® LIPIDOMIX^® Standard includes all of the major lipid classes at ratios relative to human plasma, allowing one easy internal standard solution to be added to every sample.

Legal Information

SPLASH is a registered trademark of Avanti Polar Lipids, Inc.

LIPIDOMIX is a registered trademark of Avanti Polar Lipids, Inc.

Packaging

5 mL Clear Glass Sealed Ampule (791644C-1mg)