Application

15:0-18:1-d7-PE (1-pentadecanoyl-2-oleoyl(d7)-sn-glycero-3-phosphoethanolamine) has been used: as a component of extraction solvent for lipid isolation from biological samples, as an internal standard for spiking serum samples for liquid chromatography with tandem mass spectrometry (LC-MS/MS)as an internal standard to spike plasma samples for fourier transform mass spectrometry (FTMS) analysis

Biochem/physiol Actions

Phosphatidylethanolamine (PE) regulates protein folding, protein modification, autophagy and cell division. PE serves as a substrate for glycosylphosphatidylinositol anchored proteins (GPI-APs) synthesis. Low levels of PE may be observed in Parkinson′s disease and may also inhibit protein maturation.

General description

15:0-18:1-d7-PE (1-pentadecanoyl-2-oleoyl(d7)-sn-glycero-3-phosphoethanolamine) is a deuterated phospholipid. The lipid comprises phosphatidylethanolamine attached to pentadecanoic acid and oleic acid. Oleic acid harbors the deuterium ions. Phosphatidylethanolamine is a membrane phospholipid and serves as an intermediate in other glycerophospholipidsynthesis.

This deuterium labeled lipid is also available in a formulation of multiple lipid standards. The SPLASH^® LIPIDOMIX^® Standard includes all of the major lipid classes at ratios relative to human plasma, allowing one easy internal standard solution to be added to every sample.

Legal Information

SPLASH is a registered trademark of Avanti Polar Lipids, Inc.

LIPIDOMIX is a registered trademark of Avanti Polar Lipids, Inc.

Packaging

2 mL Amber Glass Sealed Ampule (791638C-1mg)