5 ALPHA 6 BETA-DIHYDROXYCHOLESTANOL-D7

Code: 700055P-1MG D2-231

Application

5α,6β-dihydroxycholestanol-d7 has been used as an analyte in liquid chromatography with tandem mass spectrometry (LC-MS-MS) analysis based multiple reaction monit...


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€397.60 1MG
€489.05 inc. VAT
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Application

5α,6β-dihydroxycholestanol-d7 has been used as an analyte in liquid chromatography with tandem mass spectrometry (LC-MS-MS) analysis based multiple reaction monitoring (MRM) studies and as an internal standard in tandem mass spectrometry (MS/MS) for analysis of plasma samples.

Biochem/physiol Actions

5α,6β-dihydroxycholestanol (5α,6β-diOH-Chol) or cholestane-3β,5α,6β-triol (C-triol) levels are elevated along with 7-ketocholesterol in Niemann-Pick type C (NP-C) disease and is a key biomarkers for detection. It has ,neuroprotective functionality and may elicit protection against neuronal injury during ischemia.

General description

5α,6β-dihydroxycholestanol is a structural derivative of cholesterol and is an abundant oxysterols. 5α,6β-dihydroxycholestanol-d7 is a deuterated form of 5α,6β-dihydroxycholestanol.

Packaging

5 mL Amber Glass Screw Cap Vial (700055P-5mg)

5 mL Amber Glass Screw Cap Vial (700055P-1mg)

assay>99% (TLC)
formpowder
manufacturer/tradenameAvanti Polar Lipids 700055P
packagingpkg of 1 × 5 mg (700055P-5mg), pkg of 1 × 1 mg (700055P-1mg)
shipped indry ice
SMILES string[H][C@@]12[C@]([C@](CC[C@H](O)C3)(C)[C@@]3(O)[C@H](O)C2)([H])CC[C@@]4(C)[C@@]1([H])CC[C@]4([H])[C@]([H])(C)CCCC([2H])(C([2H])([2H])[2H])C([2H])([2H])[2H]
storage temp.−20°C
Cas Number127684-07-5
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