Application

4β-hydroxycholesterol-d7 has been used: as an internal standard to spike plasma samples ultra-high-pressure liquid,chromatography–tandem mass spectrometry (UHPLC-MS/MS) analysisto spike serum samples for mass spectrometry measurementsas an internal standard for the quantification of human colon biopsies samples using HPLC-MS

Biochem/physiol Actions

4β-hydroxycholesterol (4β-HC) may function as a liver X receptor ligand. The levels of 4β-HC are elevated in dextran sulfate induced colitis along with other oxysterols and it may promote colon inflammation.

General description

4β-hydroxycholesterol (4β-HC) is a catabolic product of cholesterol metabolism mediated by the enzyme cytochrome P450 family 3 subfamily A member 4 (CYP3A4). 4β-hydroxycholesterol-d7 is the deuterated form of 4β-hydroxycholesterol.

Packaging

5 mL Amber Glass Screw Cap Vial (700042P-1mg)