Lyo-Ready AOF dUTP DNA qPCR Urine (MDX352) uses an advanced one-tube formulation, incorporating the latest innovations in buffer chemistry and PCR enhancers, along with an optimised concentration of recombinant antibody-mediated hot-start polymerase, dNTPs (including dUTP), and MgCl2. Lyo-Ready AOF dUTP RNA/DNA qPCR Urine, (MDX353) also includes reverse transcriptase and RNase inhibitor for comprehensive nucleic acid detection.
Lyo-Ready AOF dUTP DNA/RNA qPCR mixes utilise the dUTP/UDGase system to prevent carryover contamination, minimising false positives and ensuring accurate results, especially in high-throughput workflows. BSA-free and sustainable, these mixes also align with evolving regulatory trends toward in vitro systems, reducing reliance on animal-sourced reagents while offering cost-effective, room-temperature stability through their lyophilisation-ready formulation.
Urine, a versatile and non-invasive clinical specimen, is increasingly used for diagnosing infectious diseases, metabolic disorders, cancer, and drug monitoring. However, inhibitors like urea and nucleases can impact accuracy. Our inhibitor-tolerant Lyo-Ready mixes ensure sensitive RNA/DNA detection, even in crude urine samples, providing reliable results for diverse diagnostic applications.
- Supports the development of urine-based screening assays, such as assays detecting sexually transmitted diseases (STDs) or urinary tract infections (UTIs)
- Enables highly sensitive detection of low-copy number bacteria, viruses, and cell-free nucleic acids directly from crude urine samples
- Facilitates quick and accurate identification of slow-growing and hard-to-culture microorganisms, reducing ambiguous results
- Offers the flexibility to remain as a liquid mix or be lyophilised, creating ambient-temperature stable assays with extended shelf life
- Highly sensitive detection of RNA/DNA, even in crude urine samples
- Incorporates dUTP, making it ideal for high-throughput and multiplex assays
- Animal-origin free and sustainable, designed to reduce environmental impact while aligning with future eco-regulations
This product has met the following criteria to qualify for the following awards: