Meridian Bioscience Lyo-Ready Direct RNA/DNA qPCR Urine 4x - 10000 Reactions

Code: MDX153-50 D2-0

Lyo-Ready Direct DNA qPCR and RNA/DNA qPCR Urine mixes are glycerol-free mixes that contain optimised excipients compatible with lyophilisation. The mixes have been designed for the development of ...


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€10,857.60 EACH
€13,354.85 inc. VAT

Lyo-Ready Direct DNA qPCR and RNA/DNA qPCR Urine mixes are glycerol-free mixes that contain optimised excipients compatible with lyophilisation. The mixes have been designed for the development of quantitative PCR urine test assays for direct detection of DNA and RNA from crudely processed human urine specimens. Can also be used wet and/or with purified nucleic acid.

Urine is an ideal clinical specimen because it is excreted in large quantities, is non-invasive, and it can be self-sampled. Urine specimens are used in the diagnosis and management of infectious diseases, bladder cancer and urinary tract infections (UTIs). However, urine contains substances such as urea and nucleases that can damage DNA or inhibit the PCR reaction.

Meridian’s new Lyo-Ready Direct Urine molecular mixes are unique in that they enable highly sensitive, very fast detection of target DNA or RNA directly from high concentrations of urine. With the CDC reporting a 30% increase in reportable sexually transmitted disease (STDs) between 2015 and 2019, these direct urine molecular mixes are ideal, as they allow less invasive sample collection (than a cervical or urethra swab) and encourage routine screening. They have been formulated specifically to overcome the inhibitors found in urine – no further optimisation is required aside from the addition of primers and probes. Furthermore, these mixes can be used in a wet format or dried down by lyophilisation to create ambient-temperature stable assays.

  • Ideal for developing screening assays for sexually transmitted diseases (STDs) and urinary tract infections (UTIs)
  • Very sensitive detection of low copy number bacteria, viruses and cell-free nucleic acids from crude urine samples
  • Quickly and accurately detect slow-growing and difficult-to-culture microorganisms, removing ambiguous results
  • Can be kept as a liquid mix or lyophilised to create ambient-temperature stable assays with an extended shelf-life

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