alpha-(4-Pyridyl N-oxide)-N-tert-butylnitrone, 99%

Application

Spin trap reagent used to measure ethanol oxidation to 1-hydroxyethyl radical (HER) which can bind to protein. Has also been used in studies of DNA methylation, iron-mediated polyunsaturated fatty acid peroxidation, and free-radical formation by Alzheimer β-amyloid peptide. The formation of hydroxyl radical in chondrocytes and cartilage has been detected using POBN.

α-(4-Pyridyl N-oxide)-N-tert-butylnitrone was used as spin trapping agent to detect:the formation of hydroxyl radical adducts during decomposition of hydrogen peroxide in the presence of nickel (II) oligopeptideshydroxyl radicals and selenide radical anions

Packaging

1 g in glass bottle