Insulin-like Growth Factor 2 (IGF-2) is a growth factor that promotes cell proliferation, differentiation, and survival, particularly during fetal development. IGF-2 also regulates tissue growth and muscle regeneration. Qkine has optimised the IGF-2 manufacture process to produce a highly bioactive protein with excellent lot-to-lot consistency for enhanced experimental reproducibility. Qkine human IGF-2 is a highly pure 7.5kDa monomer, animal origin-free (AOF) and carrier-protein-free (CF).

• High purity human IGF-2 protein (Uniprot: P01344)
• >98%, by SDS-PAGE quantitative densitometry
• 7.5kDa
• Expressed in E. coli
• Animal origin-free (AOF) and carrier protein-free
• Manufactured in Cambridge, UK laboratories
• Lyophilised from acetonitrile/TFA
• Resuspend in water at >100µg/mL, prepare single use aliquots, add carrier protein if desired and store frozen at -20 or -80°C
• Alternative protein names: insulin-like growth factor II, IGF2, IGF-II, Somatomedin-A, T3M-11-derived growth factor
• Species reactivity: human
• Species similarity: mouse - 91%, rat - 94%, porcine - 98%, bovine - 95%

Featured applications

• Enhancement of cell proliferation
• Prenatal development
• Promotion of muscle cell differentiation
• Involvement in tumor growth
• Diabetes and metabolic disorder research
• Influence in osteoblast proliferation and differentiation