Protoporphyrin IX, >=95%

Code: P8293-1G D2-231

Application

Activates soluble guanylyl cyclase.

Protoporphyrin IX has been used:as a standard in protoporphyrin assaysin fluorescence spectra analysisto treat cells in ...


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Your Price
€246.40 1G
€303.07 inc. VAT

Application

Activates soluble guanylyl cyclase.

Protoporphyrin IX has been used:as a standard in protoporphyrin assaysin fluorescence spectra analysisto treat cells in cell culture to study heme-mediated ferroportin 1 transcription

Biochem/physiol Actions

Protoporphyrin IX penetrates human erythrocytes and aids the release of oxygen from them. It forms complexes with myoglobin and hemoglobin. It is a photosensitizer used in the photodynamic therapy of cancer.

Protoporphyrin IXlevels are elevated intumorcells due tometabolism anomaliescompared to normalcells.

General description

Protoporphyrin IX belongs to the porphyrin family, which are a class of tetrapyrroles. It is the iron-free form of hemin and amphiphilic in nature. It is the precursor of heme in its biosynthetic pathway.

Protoporphyrin IX imparts red color to heme and is the major porphyrin in blood. It is synthesized from protoporphyrinogen IX in the presence of protoporphyrinogen IX oxidase.

Packaging

1 g in glass bottle

assay≥95%
fluorescenceλex 409 nm; λem 633 nm, λex 402 nm; λem 625 nm (bound to HRP)
formpowder
InChI keyKSFOVUSSGSKXFI-UJJXFSCMSA-N
InChI1S/C34H34N4O4/c1-7-21-17(3)25-13-26-19(5)23(9-11-33(39)40)31(37-26)16-32-24(10-12-34(41)42)20(6)28(38-32)15-30-22(8-2)18(4)27(36-30)14-29(21)35-25/h7-8,13-16,35,38H,1-2,9-12H2,3-6H3,(H,39,40)(H,41,42)/b25-13-,26-13-,27-14-,28-15-,29-14-,30-15-,31-16-,32-16-
Quality Level100
SMILES stringCc1c(CCC(O)=O)c2cc3[nH]c(cc4nc(cc5[nH]c(cc1n2)c(C)c5C=C)c(C)c4C=C)c(C)c3CCC(O)=O
storage temp.2-8°C
Cas Number553-12-8
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