SP Sepharose XL, Cytiva, 17-5073-01, pack of 300 mL

Analysis Note

To view the Certificate of Analysis for this product, please visit www.cytiva.com.

Application

SP Sepharose^® XL is based on a highly cross-linked, bead formed 6% Agarose matrix similar to the well established SP Sepharose^® Fast FLow media. Dextran chains are covalently coupled to the Agarose matrix and modified with sulphopropyl (SP) strong cation exchange groups through chemically stable ether bonds. The stable Agarose matrix and long, flexible chains of Dextran with bound charged groups work together to increase loading capacity whilst allowing high flow ratesWith its high loading capacities and excellent physical and chemical stability, SP Sepharose^® XL is suitable for the capture stage of a downstream process, which is characterised by large loads of crude samples.As member of the BioProcess media range, SP Sepharose^® XL meets industrial demands with security of supply and comprehensive technical and regulatory support.

Features and Benefits

High loading capacities give more productive capture from clarified feedstocks. Strong cation exchanger designed for capture steps High chemical stability for effective CIP/sanitization The hydrophilic nature of the base matrix ensures Low levels of non-specific binding leading to Low levels of host cell-derived impurities in the elution pool.

General description

SP Sepharose^® XL is a strong cation exchanger designed for use in the capture steps of biomolecules from clarified feed-stocks.

Legal Information

Sepharose is a registered trademark of Cytiva

Storage and Stability

Store at 4 to 30 °C (20% Ethanol + 0.2 M Sodium Acetate)