Application
Convenient form of anhydrous HF, stable up to 50°C. Has been used for the preparation of β-fluoroamines from amino alcohols and for the fluorination of acetylenes.Used together with hypervalent iodine(III) reagents for ipso-fluorination of para-substituted phenols providing cyclohexadienones. Employed with Selectfluor™ (Catalog No. 439479) for geminal fluorination of 2,2-diaryl-1,3-dithiolanes.
Reactant for preparation of:•Epimers of shikimic acid with the features of fucosylated glycans via zinc-mediated reductive ring opening followed by a Barbier reaction•Vaccinia H1-related (VHR) phosphatase inhibitor with a nonacidic phosphate-mimicking core structure•Candidates for nucleic acid drugs•ω-substituted gem-difluoroalkanes by oxidative desulfurization-difluorinationReagent for:•Halofluorination reactions
General description
May contain or form low levels of calcium fluoride during storage. Presence of this does not impact the specification values.
Legal Information
Selectfluor is a registered trademark of Merck KGaA, Darmstadt, Germany
Sure/Pac is a trademark of Sigma-Aldrich Co. LLC
Packaging
25, 100 g in poly bottle
This product has met the following criteria to qualify for the following awards: