CyJohnPhos, 97%

Code: 638099-5G D2-231

Application

Ligand employed in the palladium-catalysed synthesis of 1,3,5-tris(2′-aminophenyl)benzene, a core building block for potential ionic receptors.

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€182.00 5G
€223.86 inc. VAT

Application

Ligand employed in the palladium-catalysed synthesis of 1,3,5-tris(2′-aminophenyl)benzene, a core building block for potential ionic receptors.

Ligand for amination of aryl halides and triflates.

CyJohnPhos may be used in combination with a nickel catalyst for the Suzuki-Miyaura arylation of tertiary benzylic acetates with aryl boroxines to produce diaryl and triaryl quaternary stereocenters.

General description

CyJohnPhos [(2-Biphenyl)dicyclohexylphosphine] is an air-stable, bulky and electron-rich monodentate biarylphosphine ligand developed by the Buchwald group to enhance the reactivity of palladium catalysis during cross-coupling reactions.

Legal Information

Usage subject to US Patents 6307087 and 6395916.

Packaging

1, 5, 25 g in glass bottle

assay97%
functional groupphosphine
InChI keyLCSNDSFWVKMJCT-UHFFFAOYSA-N
InChI1S/C24H31P/c1-4-12-20(13-5-1)23-18-10-11-19-24(23)25(21-14-6-2-7-15-21)22-16-8-3-9-17-22/h1,4-5,10-13,18-19,21-22H,2-3,6-9,14-17H2
mp102-106 °C (lit.)
Quality Level100
reaction suitabilityreagent type: ligandreaction type: C-X Bond Formation, reagent type: ligandreaction type: Buchwald-Hartwig Cross Coupling Reaction, reaction type: Cross Couplings, reagent type: ligandreaction type: Hiyama Coupling, reagent type: ligandreaction type: Oxidations, reagent type: ligandreaction type: Methylations, reagent type: ligandreaction type: Arylations, reagent type: ligandreaction type: Negishi Coupling, reagent type: ligandreaction type: Suzuki-Miyaura Coupling
SMILES stringC1CCC(CC1)P(C2CCCCC2)c3ccccc3-c4ccccc4
Cas Number247940-06-3
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