CETIRIZINE HYDROCHLORIDE

Code: PHR1656-1G D2-231

Analysis Note

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

Application

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€113.40 1G
€139.48 inc. VAT

Analysis Note

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

Application

Cetirizine Hydrochloride may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by various chromatography techniques.

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Biochem/physiol Actions

Cetirizine hydrochloride is an orally active and selective H1-receptor antagonist. Antihistaminic; Piperazines. Non-sedating type histamine H1-receptor antagonist; major metabolite of hydroxyzine. Pharmacological activity resides primarily in the (R)-isomer.

Footnote

To see an example of a Certificate of Analysis for this material enter LRAA5757 in the slot below. This is an example certificate only and may not be the lot that you receive.

General description

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.Cetirizine hydrochloride, a second generation antihistaminic drug, is one of the carboxylated metabolites of hydroxyzine that can typically bind to histamine H1 receptor. It is effective against diseases such as urticaria, angioedema, allergies and hay fever.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

agencytraceable to Ph. Eur. C0980650, traceable to BP 837, traceable to USP 1102929
application(s)pharmaceutical (small molecule)
CofAcurrent certificate can be downloaded
formatneat
Gene Informationhuman ... HRH1(3269)
gradepharmaceutical secondary standard, certified reference material
InChI keyPGLIUCLTXOYQMV-UHFFFAOYSA-N
InChI1S/C21H25ClN2O3.2ClH/c22-19-8-6-18(7-9-19)21(17-4-2-1-3-5-17)24-12-10-23(11-13-24)14-15-27-16-20(25)26;;/h1-9,21H,10-16H2,(H,25,26);2*1H
packagingpkg of 1 g
Quality Level300
SMILES stringOC(COCCN1CCN(C(C2=CC=C(Cl)C=C2)C3=CC=CC=C3)CC1)=O.[H]Cl.[H]Cl
storage temp.2-30°C
technique(s)gas chromatography (GC): suitable, HPLC: suitable
Cas Number83881-52-1
This product has met the following criteria to qualify for the following awards:



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