Analysis Note

Color (visual): white to yellow to beigeAppearance of substance (visual): beadsLoading (determined from the substitution of the Fmoc-Leu loaded resin): 0.30 - 0.50 mmol/gSwelling Volume (in DMF): lot specific resultTNBS-Test (positive): passes testTNBS-Test (after loading with Fmoc-Leu-OH (negative)): passes testThe polymer matrix is copoly (styrene - 1% DVB), 100 - 200 mesh.

General description

Novabiochem^®′s AM resin is prepared according to optimized protocols by direct aminomethylation of polystyrene [1]. This process gives a highly homogeneous and chemically defined support free from potentially reactive chloromethyl groups. This resin can be easily acylated with any appropriate carboxylic acid-containing linker using standard methods of amide bond formation to furnish supports for both Boc and Fmoc batch SPPS and SPOS.

The product number for this product was previously 01-64-0447.

To obtain a certificate of analysis (CoA) of a lot that begins with the letter “A”, please select the option in the right hand menu “Request a COA for Lot#s starting with A”.

Legal Information

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

Linkage

Replaces: 01-64-0447