HYDROXYMETHYL POLYSTYRENE (100-200 MESH); 1% DVB

Code: 8550680005 D2-231

Analysis Note

Color (visual): white to yellow to beigeAppearance of substance (visual): beadsLoading (determined from the substitution of the Fmoc-Leu loaded resin): 0.60 - 1...


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Your Price
€72.70 EACH
€89.42 inc. VAT

Analysis Note

Color (visual): white to yellow to beigeAppearance of substance (visual): beadsLoading (determined from the substitution of the Fmoc-Leu loaded resin): 0.60 - 1.60 mmol/gSwelling Volume (in DMF): lot specific resultThe polymer matrix is copoly (styrene - 1% DVB) 100 -200 mesh

General description

This resin is ideal for the solid phase immobilization of carboxylic acids. Less cross-linking is observed than with Merrifield resin during the attachment of diacids [1]. Reaction with a suitable phosgene equivalent converts this resin to a support suitable for the immobilization of amines [2].

Release of carboxylic acids from this support is normally effected by treatment of the resin with HF or TFMSA, or by hydrogenolysis [3]. Alcohols can be liberated by reduction with DIBAL [4] or LiBH4 [5]. Methyl esters can be produced by transesterification with MeONa [6] or Ti(OEt)4/C2H5CO2Me [7]. Carboxamides are also accessible via Lewis acid catalyzed aminolysis [8].

The product number for this product was previously 01-64-0110.

To obtain a certificate of analysis (CoA) of a lot that begins with the letter “A”, please select the option in the right hand menu “Request a COA for Lot#s starting with A”.

Legal Information

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

Linkage

Replaces: 01-64-0110

Packaging

25 g in Plastic bottle

application(s)peptide synthesis
formbeads
functional groupalcohol
manufacturer/tradenameNovabiochem®
Quality Level200
reaction suitabilityreaction type: Boc solid-phase peptide synthesis
storage temp.2-30°C
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