Analysis Note

Colour (visual): white to slight yellow to beigeAppearance of substance (visual): powderIdentity (IR): passes testAssay (HPLC, area%): ≥ 90.0 % (a/a)Ethyl acetate (HS-GC): ≤ 0.5 ¬etate (IC): ≤ 0.1 %

General description

Building block [1] for the introduction by Fmoc SPPS of the hydrolytically stable phosphotyrosine analog phosphonodifluoromethylphenylalanine (F₂Pmp) [2]. The pKa of F₂Pmp more closely resembles that of a phosphate group making it better analog than phosphonomethylphenylalanine.

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