Analysis Note

Color (visual): white to slight yellow to beigeAppearance of substance (visual): powderIdentity (IR): passes testOptical rotation α 25/D (c=1 in methanol): -26.5 - -21.5 °Purity (TLC(0811)): ≥ 97 %Assay (HPLC, area%): ≥ 97.0 % (a/a)Solubility (1 mmole in 2 ml DMF): clearly solubleAssay (acidimetric): ≥ 90.0 %Water (K. F.): ≤ 2.00 %For TLC-Systems see our General Catalog

General description

Fmoc-Aaa-(Dmb)Gly-OH dipeptides offer the same benefits as pseudoproline dipeptides but for peptide sequences containing Gly. They are extremely easy to use. Standard coupling methods like PyBOP^®/DIPEA or DIPCDI/HOBt can be used for their introduction. Removal of the Dmb group and regeneration of the glycine residue occurs during the course of standard TFA-mediated cleavage reaction.



The product number for this product was previously 04-12-1265.

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Legal Information

PyBOP is a registered trademark of Merck KGaA, Darmstadt, Germany

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

Linkage

Replaces: 04-12-1265