Analysis Note

Color (visual): white to slight yellow to beigeAppearance of substance (visual): powderIdentity (IR): passes testAssay (HPLC, area%): ≥ 99.0 % (a/a)Solubility (10% in acetonitrile): clear

General description

COMU is a novel reagent which mediates coupling reactions with efficiencies comparable to HATU [1, 2].

It has higher solubility than HATU and HBTU. Furthermore, it is not explosive under normal operating conditions and is less likely to exhibit allergenicity compared to other coupling reagents. Recently, the application of COMU in the preparation of esters has been demonstrated [3].

Legal Information

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