A7154-25MG Display Image

Adenosine, periodate oxidized, >=93%

Code: A7154-25MG D2-231

Application

Adenosine, periodate oxidized has been used: as a methylarginine transferase inhibitor in the human embryonic kidney (HEK)-293 T cells as a methylase inhibitor in...


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€185.31 25MG
€227.93 inc. VAT
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Application

Adenosine, periodate oxidized has been used: as a methylarginine transferase inhibitor in the human embryonic kidney (HEK)-293 T cells as a methylase inhibitor in H4 neurogliomaas a broad inhibitor of S-adenosylmethionine (AdoMet)-dependent methyltransferases in mouse embryo fibroblast NIH3T3 cells

Biochem/physiol Actions

Adenosine, periodate oxidized (Adox) is a protein arginine methyltransferases (PRMTs) inhibitor. It also inhibits the enzyme S-adenosylhomocysteine hydrolase and induces apoptosis. Its inhibitory effect on histone methyltransferases prevents histone methylation. Adox also elicits intrinsic cytotoxic properties.

Packaging

25, 100 mg in poly bottle

assay≥93%
biological sourcesynthetic (organic)
formpowder
InChI keyILMNSCQOSGKTNZ-UHFFFAOYSA-N
InChI1S/C10H11N5O4/c11-9-8-10(13-4-12-9)15(5-14-8)7(3-18)19-6(1-16)2-17/h1,3-7,17H,2H2,(H2,11,12,13)
Quality Level200
SMILES stringNc1ncnc2n(cnc12)C(OC(CO)C=O)C=O
solubility0.2 M HCl: 50 mg/mL, clear, colorless to faintly yellow
storage temp.−20°C
Cas Number34240-05-6
This product has met the following criteria: