Adenosine,

Code: 01890-25G D2-231

Biochem/physiol Actions

Endogenous neurotransmitter at adenosine receptors. Cardioprotective effects may relate to activation of A1 adenosine receptors. The antipl...


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€121.20 25G
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Biochem/physiol Actions

Endogenous neurotransmitter at adenosine receptors. Cardioprotective effects may relate to activation of A1 adenosine receptors. The antiplatelet and anti−inflammatory actions of adenosine appear to be mediated via the A2 adenosine receptor. In contrast, adenosine appears to be a pro-inflammatory mediator in asthma and chronic obstructive pulmonary disease (COPD).

Other Notes

Substrate for the assay of adenosine deaminase

cation tracesCr: ≤5 mg/kg, Mn: ≤5 mg/kg, Ca: ≤10 mg/kg, Pb: ≤5 mg/kg, Mg: ≤20 mg/kg, Cu: ≤5 mg/kg, Fe: ≤5 mg/kg, Zn: ≤5 mg/kg, Ni: ≤5 mg/kg, Cd: ≤5 mg/kg, Co: ≤5 mg/kg
formpowder
Gene Informationhuman ... ADORA1(134), ADORA2A(135), ADORA2B(136), ADORA3(140)
ign. residue≤0.1% (as SO4)
InChI keyOIRDTQYFTABQOQ-KQYNXXCUSA-N
InChI1S/C10H13N5O4/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(18)6(17)4(1-16)19-10/h2-4,6-7,10,16-18H,1H2,(H2,11,12,13)/t4-,6-,7-,10-/m1/s1
mp234-236 °C (lit.)
optical activity[α]20/D −70±3°, c = 2% in 5% NaOH
Quality Level200
SMILES stringNc1ncnc2n(cnc12)[C@@H]3O[C@H](CO)[C@@H](O)[C@H]3O
storage temp.2-8°C
Cas Number58-61-7
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