Application

p-Toluenesulfonylmethyl isocyanide was used:in the synthesis of triplet drugs with the 1,3,5-trioxazatriquinane skeletonas reagent in the preparation of biologically active pyrroles and imidazolesas the isonitrile component in a diastereoselective Passerini reaction employing sugar-derived aldehydes

General description

p-Toluenesulfonylmethyl isocyanide undergoes base-promoted 1,3-dipolar cycloaddition reaction with immobilized imines under microwave irradiation to yield 1,5-disubstituted imidazoles. It is a versatile synthon in organic chemistry, extensively used for the synthesis of heterocyclic compounds.

Packaging

5, 25 g in glass bottle