3-Methyl-2-oxindole, 96%

Application

•Reactant for enantioselective A-amination reactions•Reactant for aldol reaction with glyoxal derivatives•Reactant for amine thiourea catalyzed conjugate addition to A,β-unsaturated aldehydes•Reactant for O-acetylation reactions•Reactant for preparation of a disubstituted oxoindole by using rhodium-catalyzed cyclopropanation/ring-opening reactions

3-Methyl-2-oxindole may be used in the preparation of 3-hydroxy-3-methyl-2-oxindole.

General description

3-Methyl-2-oxindole (MOI) is a 3-substituted-2-oxindole. It is reported to be formed during the oxidation of indole-3-acetic acid in the presence of Fe^II under aerobic conditions. MOI undergoes asymmetric anti-Mannich-type reaction with N-tosyl aryl aldimines in the presence of alkaloid cinchona derivatives to form anti-3,3-disubsituted 2-oxindole derivatives. It also undergoes asymmetric hydroxyamination with nitrosoarenes to form N-nitroso aldol products.

Packaging

5, 25 g in glass bottle