Application

Analytes: CD31 (sPecam-1), sE-Selectin, sICAM-1, PAI-1 (Total), ProMMP-9, sP-Selectin, Thrombomodulin, s Recommended Sample Type: Mouse serum, plasma or cell/tissue culture supernatants or lysates Recommended Sample Dilution: 25 µL per well of 1:20 diluted serum or plasma; cell/tissue culture samples may require dilution in appropriate control mediumAssay Run Time: Overnight (16-18 hours) at 2-8°C Research Category: Cardiovascular Disease Research Subcategory: Metabolism

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Features and Benefits

Design your multiplex kit by choosing available analytes within this panel.

General description

Cardiovascular disease, particularly atherosclerotic vascular disease, is a leading cause of global mortality, accounting for 30% of all global deaths (WHO, 2010). Inflammatory mechanisms play a vital role in the initiation, maintenance, and progression of vascular disease with a strong correlation between inflammatory markers and prognosis in acute and chronic coronary artery disease. Numerous studies have demonstrated an association of obesity and diabetes with cardiovascular risk factors. MILLIPLEX^® Mouse CVD Panel 1 is a 7-plex kit to be used for the simultaneous quantification of any or all of the following analytes in serum and plasma samples: sE-Selectin, sICAM-1, Pecam-1, sP-Selectin, PAI-1 Total, proMMP-9, and Thrombomodulin. This kit uses a 96-well format, contains a lyophilized standard cocktail, two internal assay quality controls and can measure up to 38 samples in duplicate. The Luminex^® xMAP^® platform uses a magnetic bead immunoassay format for ideal speed and sensitivity to quantitate multiple analytes simultaneously, dramatically improving productivity while conserving valuable sample volume. Panel Type: Cardiovascular

Legal Information

xMAP is a registered trademark of Luminex Corp

Luminex is a registered trademark of Luminex Corp

MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany

Other Notes

Please contact Technical Service for linearity of dilution.

Specificity

Cross ReactivtyNon-detectable within the panel