Application

Analytes: Tau (Total), Amyloid β40, Amyloid β42, Tau (pThr181) Recommended Sample type: cerebrospinal fluid (CSF) Recommended Sample dilution: 1:2 sample dilution is recommended for extracted CSF samples Assay Run Time: Overnight Research Category: Neuroscience Metabolism Research Subcategory: Metabolic Disorders Obesity Inflammation & Autoimmune Mechanisms Research Category Neuroscience Metabolism NOTE: This is a competitive assay

Components

Human ABeta and Tau Standard, 1 vial, lyophilizedHuman ABeta and Tau Quality Control 1, 1 vial, lyophilizedHuman ABeta and Tau Quality Control 2, 1 vial, lyophilizedBead Diluent, 1 bottle, 3.5mLSet of one 96-Well Plate with 2 sealersAssay Buffer, 1 bottle, 30 mLWash Buffer, 10X (0.05% Proclin), 2 bottles, 30 mL eaHuman ABeta and Tau Detection Antibodies, 1 bottle, 3.2 mLStreptavidin-Phycoerythrin, 1 bottle, 3.2 mLMixing Bottle, 1 bottle

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Features and Benefits

Design your multiplex kit by choosing available analytes within this panel.

General description

MILLIPLEX^® Human Amyloid Beta and Tau Panel enables you to focus on the relevance and therapeutic potential of Aβ40, Aβ42, Total Tau proteins (tTau), and Phosphorylated Tau Thr181 (pTau181) in your research model. Coupled with the Luminex^® xMAP^® platform in a bead format, you receive the advantage of ideal speed and sensitivity, allowing quantitative multiplex detection of multiple analytes simultaneously, which can dramatically improve productivity. The MILLIPLEX^® Human Amyloid Beta Tau Bead Panel is to be used for the simultaneous quantification of Aβ40, Aβ42, tTau, and pTau181. This kit may be used only for the analysis of cerebrospinal fluid (CSF). This is a configurable assay, and some or all analytes can be selected: tau (total), amyloid β40, amyloid β42 and tau (pThr181). MILLIPLEX^® portfolio offers the broadest selection of analytes across a wide range of disease states and species. Once the analytes of interest have been identified, you can rely on the quality that we build into each kit to produce results you can trust. In addition to the assay characteristics listed in the protocol, other performance criteria evaluated during the validation process include: cross-reactivity, dilution linearity, kit stability and sample behavior (e.g. detectability and stability). Each panel and kit meets stringent manufacturing criteria to ensure batch-to-batch reproducibility. Each MILLIPLEX^® panel and kit includes: Quality controls (QCs) provided to qualify assay performance Comparison of standard (calibrator) and QC lots to a reference lot to ensure lot-to-lot consistency Optimized serum matrix to mimic native analyte environment Detection antibody cocktails designed to yield consistent analyte profiles within panel MILLIPLEX^® Human Amyloid Beta Tau Bead Panel is part of the most versatile system available for cytokine research. From our single to multiplex biomarker solutions, we partner with you to design, develop, analytically validate, and build the most comprehensive library available for protein detection and quantitation. Panel Type: Neuroscience

Legal Information

xMAP is a registered trademark of Luminex Corp

Luminex is a registered trademark of Luminex Corp

MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany

Packaging

96-well plate

Everything you need in a single kit.

Specificity

Cross ReactivtyThere was no or negligible cross-reactivity between the antibodies for an analyte and any of the other analytes within a panel.

Storage and Stability

Recommended storage for kit components is 2 - 8°C.