Application
Analytes: BAFF/Blys, BRAK/CXCL14, CCL28, CXCL16, HCC-4/CCL16, HMGB1, IFNβ, IL-14, IL-19, IL-24, IL-28B, IL-32α, IL-34, IL-35, IL-36β/IL-1F8, IL-37/IL-1F7, IL-38/IL-1F10, MIP-4, MPIF/CCL23, YKL40 Recommended Sample type: Serum, plasma, and tissue/cell culture supernatant Recommended Sample dilution: 1:4 diluted serum or plasma. Tissue culture supernatant may require a dilution with an appropriate control medium prior to assay Assay Run Time: Overnight or two-hour primary incubation assay. For best results, an overnight incubation is recommended. Research Category: Inflammation & Immunology NOTE: HMGB1 can be measured in serum and plasma samples only
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Features and Benefits
Design your multiplex kit by choosing available analytes within this panel.
General description
“Cytokine” is a general term used for a diverse group of soluble proteins and peptides which act as regulators under both normal and pathological conditions to modulate the functional activities of individual cells and tissues. These proteins also mediate direct interactions between cells and regulate processes taking place in the extracellular environment. The cytokine group of proteins includes lymphokines, interferons, colony stimulating factors and chemokines. Cytokine and chemokine research plays a significant role in achieving a deeper understanding of the immune system and its multi-faceted response to most antigens, as well as disease states such as inflammatory disease, allergic reactions, irritable bowel disease (IBD), sepsis, and cancer. The MILLIPLEX® Human Cytokine / Chemokine Panel 4 enables you to focus on the therapeutic potential of cytokines as well as the modulation of cytokine expression. The Luminex® xMAP® platform uses a magnetic bead immunoassay format for ideal speed and sensitivity to quantitate multiple analytes simultaneously, dramatically improving productivity while conserving valuable sample volume. Panel Type: Cytokines/Chemokines
Legal Information
xMAP is a registered trademark of Luminex Corp
Luminex is a registered trademark of Luminex Corp
MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany
Other Notes
Please note: Sample Type must be selected when configuring this kit. HMGB1 can be measured in serum and plasma samples only.
Packaging
96 well plate
Specificity
Cross-reactivity between the antibodies and any of the other analytes in this panel is non-detectable or negligible.
Storage and Stability
Recommended storage for kit components is 2 - 8°C.
This product has met the following criteria to qualify for the following awards: