Application

Chlorotriethylsilane may be used as a derivatizing reagent for the determination of fluoride, in toothpaste samples using headspace solid-phase micrŒxtraction and gas chromatography–flame ionization detection.

General description

Chlorotriethylsilane may be used as a silylating reagent for the preparation of trisilyl ethers from alcohols in the presence of a base such as imidazole, pyridine or 4-(dimethylamino)pyridine. It is found to be more reactive when used with pyridine as a solvent.

Legal Information

LiChropur is a trademark of Merck KGaA, Darmstadt, Germany

Other Notes

Silylating agent with some advantage over the trimethylsilylating agents for synthetic and analytical applications