(R,R)-(-)-2,3-Bis(tert-butylmethylphosphino)quinoxaline, 97%

Application

Air-Stable and Highly Efficient Chiral Ligands

Efficient ligand exhibiting high levels of enantiocontrol in synthetic transformations ranging from metal-catalyzed 1,4-addition of arylboronic acids to alkylative ring opening to asymmetric hydrogenation.

Citation

Yahav-Levi A, et al. "Aryl-bromide reductive elimination from an isolated Pt (IV) complex." Chemical Communications 46(19) (2010): 3324-3326.

Imamoto T, et al. "Highly enantioselective hydrosilylation of simple ketones catalyzed by rhodium complexes of P-chiral diphosphine ligands bearing tert-butylmethylphosphino groups." Tetrahedron: Asymmetry 17(4) (2006): 560-565.

Fang P and Hou XL. "Asymmetric Copper-Catalyzed Propargylic Substitution Reaction of Propargylic Acetates with Enamines." Organic letters 11.20 (2009): 4612-4615.

Features and Benefits

Advantages of the QuinoxP* Ligands: It is not oxidized nor epimerized at ambient conditions in air Enantioselectivities are outstanding for various reaction paradigms Hydrogenations proceed under mild reaction conditions Low catalyst loadings yield high TONs

General description

(R,R)-(-)-2,3-Bis(tert-butylmethylphosphino)quinoxaline is an air-stable C₂-symmetric P-stereogenic phosphine ligand.

Legal Information

QuinoxP is a registered trademark of Nippon Chemical Industry Co., Ltd.

Packaging

100 mg in clear glass bottle

500 mg in amber glass bottle