(DHQ)2PHAL, >=95%

Application

Ligand for Sharpless Asymmetric Dihydroxylation employed in an enantioselective preparation of syn-3,5-hydroxycarboxylates from (E,E)- or (E,Z)-1,3-dienoates.

(DHQ)₂PHAL may be used in the following processes:As a catalyst Asymmetric and chemoselective N-allylic alkylation of indoles with Morita-Baylis-Hillman carbonates to form pyrrolo[1,2-a]indole and pyrrolo[3,2,1-ij]quinoline derivatives.As a ligand for the osmium catalyzed-Sharpless asymmetric dihydroxylation step of (S)-a-benzoyloxy carboxylic acids multistep synthesis.As a ligand for the carbamate based asymmetric aminohydroxylation of styrene derivatives to form N-carbamate protected R-arylglycinols.

General description

DHQ)₂PHAL is a modified cinchona alkaloid.

Packaging

500 mg in glass bottle

Physical form

Asymmetric dihydroxylation of unsaturated esters with trisubstituted C=C bonds.