Analysis Note

Endotoxin tested

Application

Human serum from platelet poor plasma (PPP) is useful for studies of the effects of platelet lysates on the growth of cells such as articular chondrocytes and human skin fibroblasts. It has also been used in platelet derived growth factor (PDGF) purification assays.

Human Serum has been used:in the preparation of human serum samples that mimic the COVID-19 patient samples for serological antibody testingas a media supplement to differentiate human induced pluripotent stem cells (hiPS) to hiPS- brain microvascular endothelial cells (BMEC)for culturing transgenic Plasmodium falciparum clonefor assessing the electrochemical response of recombinant P. falciparum parasite L-lactate dehydrogenase (LDH) in serum samplesin platelet-derived growth factor (PDGF) purification assays

Biochem/physiol Actions

Serum serves as a supplement to basal media formulations and conventional biomedical cell culture media. It acts as a source of trace nutrients, signaling molecules, growth factors, and hormones that induce proper cell growth in vitro. Human serum from platelet-poor plasma (PPP) is useful in the studies of the effects of platelet lysates on the growth of cells such as articular chondrocytes and human skin fibroblasts.

General description

The serum is the fluid part of the blood containing plasma without fibrinogen.

Other Notes

It is not unusual for a white precipitate to form following a freeze-thaw cycle for this human serum product.