Analysis Note

ControlHeLa cells.

Application

Research CategoryStem Cell Research

Research Sub CategoryMesenchymal Stem Cells

Detect BMP-7 using this Milli-Mark Anti-BMP-7-FITC Antibody, clone 2A10 validated for use in FC.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

General description

Bone morphogenetic protein-7 (BMP-7), also known as osteogenic protein-1, is a member of the TGF- superfamily, and is widely expressed during embryonic development. Like other members of the bone morphogenetic protein family, BMP-7 works synergistically with BMP-2 to play a key role in the differentiation of mesenchymal cells into bone and cartilage tissues by actively recruiting stem cells from the surrounding tissue, thereby initiating the bone formation cascade. In adult cells, BMP-7 is predominately expressed in the brain, kidneys, and bladder.

Immunogen

Epitope: Unknown

Recombinant full-length BMP-7 protein.

Legal Information

MILLI-MARK is a registered trademark of Merck KGaA, Darmstadt, Germany

Other Notes

Unconjugated antibody (MAB4350) also reacts against Mouse.

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Physical form

Protein G Purified

Purified mouse monoclonal IgG1κ conjugated to FITC in PBS with 0.1% sodium azide and 15 mg/mL BSA.

Quality

Evaluated by flow cytometry using HeLa cells.

Specificity

This monoclonal antibody recognizes BMP-7.

Storage and Stability

Stable for 1 year at 2-8°C from date of receipt.

Target description

46kDa Observed