Biochem/physiol Actions

Shown to bind to P-selectin ligands on U937 cells.

General description

Recombinant, human P-selectin consisting of 730 amino acids minus the transmembrane and cytoplasmic domains expressed in CHO cells. This glycoprotein is expressed on activated platelets and endothelial cells. A specific interaction between P-selectin and P-selectin glycoprotein ligand-1, present on numerous cell types, promotes adhesion and acts along with L-selectin in establishing an initial interaction between circulating leukocytes and the endothelium.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Packaging

50 µg in Plastic ampoule

Physical form

Lyophilized from Dulbecco's D-PBS (containing calcium and magnesium), 1% sorbitol.

Reconstitution

Reconstitute at 1 mg/ml in sterile H₂O.

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C.

Warning

Toxicity: Standard Handling (A)