General description

Recombinant human galectin-1 expressed in and purified from E. coli. Galectins are a family of evolutionarily conserved animal lectins with affinity for β-galactosides that have homologous carbohydrate recognition domains (CRDs). Galectin-1 can induce apoptosis of activated T cells and leukemic T cell lines. It also binds to CD45 and inhibits its protein phosphatase activity.

Recombinant, human galectin-1 expressed in E. coli. Galectins are a family of evolutionarily conserved animal lectins with affinity for β-galactosides that have homologous carbohydrate recognition domains (CRDs). Galectin-1 can induce apoptosis of activated T cells and leukemic T cell lines. It also binds to CD45 and inhibits its protein phosphatase activity.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Other Notes

Rabinovich, A., et al. 2002. Trends Immunol.23, 313.Rabinovich, A., et al. 2002. J. Leukoc. Biol.71, 741.Hughes, R.C., et al. 2001. Biochimie.83, 667.

Packaging

50 µg in Plastic ampoule

Physical form

Lyophilized from sterile-filtered 20 mM Tris-HCl, pH 7.5.

Preparation Note

Further dilute into aqueous buffers as needed.

Reconstitution

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C. Diluted working solutions are stable for up to 1 week at 4°C or for up to 1 month at -20°C.

Warning

Toxicity: Standard Handling (A)