N-Maleoyl-beta-alanine, 97%

Application

N-Maleoyl-β-alanine (3-maleimidopropanoic acid, N-(2-carboxyethyl)maleimide)) is the suitable reagent used in the following studies:To decrease the biotin binding affinity of Avd(S16C) (avidin with a single point mutation S16C).As a side chain reactive agent to modify tryptic peptides that result in mass shifts indicating the presence of cysteine residues.To preblock Xenopus laevis oocytes for exposed cysteines used as an expression system in the study of conformational changes in cASIC1a Receptors.It may be used in the following studies:As a protective agent for keratin fiber in high temperature process.As a non-cleavable maleimido moiety during the synthesis of tetrawalled molecular umbrella-octaarginine conjugates.Synthesis of organotin carboxylates of N-Maleoyl-β-alanine.To functionalize the gold surfaces to interact with cysteine-modified peptide.Preparation of cross-linked dextran–poly(ethylene glycol) hydrogel substrate.

General description

N-Maleoyl-β-alanine (3-maleimidopropanoic acid) is an aliphatic N-substituted maleimide. It is one of the component of the stabilizing solution for EC145 (a folate-targeted vinca alkaloid conjugate) used in rodent pharmacokinetic studies.

Packaging

1 g in glass bottle

250 mg in glass bottle

Bottomless glass bottle. Contents are inside inserted fused cone.