Application

4-Pentynoic acid was used:as building block for the synthesis of library of eight sequence-defined model oligomersin one-pot synthesis of the complex polycyclic heterocycles benzo[4,5]imidazo[1,2-c]pyrrolo[1,2-a]quinazolinone derivativesin the synthesis of various allenenols lactones [5(E)-(2-allenylidene)-tetrahydro-2-furanones]in the synthesis of a cyctotoxic macrolide by ring-closing metathesis of a bis acetylene

General description

4-Pentynoic acid undergoes copper-catalyzed intramolecular cyclizations to form enol lactones. It also reacts with 1-bromo-1-alkynes in the presence of a Pd catalyst to yield biologically active ynenol lactones.

Packaging

1, 5 g in glass bottle