2,4,3,5-tetramethoxystilbene, >=98% (HPLC)

Code: SMB00388-10MG D2-231

Biochem/physiol Actions

2,3′,4,5′-Tetramethoxystilbene, also known as TMS, is a selective and competitive inhibitor of cytochrome P450 1B. It is a synthetic trans-stilbene an...


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€147.00 10MG
€180.81 inc. VAT
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Biochem/physiol Actions

2,3′,4,5′-Tetramethoxystilbene, also known as TMS, is a selective and competitive inhibitor of cytochrome P450 1B. It is a synthetic trans-stilbene analog. TMS is an analog of resveratrol and is an anti-cancer agent. TMS is cytotoxic to gefitinib-resistant (G-R) non-small-cell lung cancer (NSCLC) cells. It binds to sarco/endoplasmic reticulum Ca2+-ATPase (SERCA) and promotes apoptosis and autophagy. TMS is also a selective inhibitor of CYP1B1.

Packaging

10 mg in glass bottle

50 mg in poly bottle

assay≥98% (HPLC)
colorwhite to yellow
formpowder
InChI keyJDBCWSHYEQUBLW-AATRIKPKSA-N
InChI1S/C18H20O4/c1-19-15-8-7-14(18(12-15)22-4)6-5-13-9-16(20-2)11-17(10-13)21-3/h5-12H,1-4H3/b6-5+
Quality Level200
SMILES stringCOC1=CC(OC)=CC=C1/C=C/C2=CC(OC)=CC(OC)=C2
storage temp.−20°C
technique(s)HPLC: suitable
Cas Number24144-92-1
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