Spiramycin,

Code: S9132-1G D2-231

Application

Spiramycin is a macrolide antibiotic that is commonly used to treat infections of soft tissues. It has been used to treat bronchopulmonary infections in adults a...


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Application

Spiramycin is a macrolide antibiotic that is commonly used to treat infections of soft tissues. It has been used to treat bronchopulmonary infections in adults and has been used to study septicemia in mice .

Biochem/physiol Actions

Spiramycin is a 16-membered ring macrolide antibiotic from Streptomyces ambofaciens. It inhibits bacterial protein synthesis at the level of peptidy-tRNA dissociation from ribosomes. It is mainly used against Gram-positive bacteria.

General description

Chemical structure: macrolide

Other Notes

Keep container tightly closed in a dry and well-ventilated place.

Packaging

1, 5 g in poly bottle

Quality

A mixture of Spiramycin I, II and III.

antibiotic activity spectrumGram-positive bacteria
cation tracesheavy metals: ≤20 ppm
colorwhite to light yellow
formpowder
InChI keyACTOXUHEUCPTEW-JMRHEKERSA-N
InChI1S/C43H74N2O14/c1-24-21-29(19-20-46)39(59-42-37(49)36(45(9)10)38(27(4)56-42)58-35-23-43(6,51)41(50)28(5)55-35)40(52-11)31(47)22-33(48)53-25(2)15-13-12-14-16-32(24)57-34-18-17-30(44(7)8)26(3)54-34/h12-14,16,20,24-32,34-42,47,49-51H,15,17-19,21-23H2,1-11H3/b13-12+,16-14+/t24-,25-,26?,27?,28?,29+,30?,31-,32+,34?,35?,36?,37?,38?,39+,40+,41?,42?,43?/m1/s1
mode of actionprotein synthesis | interferes
optical activity[α]/D -85 to -80° in water (Specific rotation (dry basis))
potency≥4100 I.U. per mg (dry basis)
Quality Level200
SMILES stringCO[C@H]1[C@H](O)CC(=O)O[C@H](C)CC=CC=C[C@H](OC2CCC(C(C)O2)N(C)C)[C@H](C)C[C@H](CC=O)[C@@H]1OC3OC(C)C(OC4CC(C)(O)C(O)C(C)O4)C(C3O)N(C)C
solubilitymethanol: soluble
storage condition(Keep container tightly closed in a dry and well-ventilated place.)
storage temp.2-8°C
Cas Number8025-81-8
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