Swainsonine, from Metarrhizium anisopliae, >=98% (TLC)

Code: S8195-1MG D2-231

Application

Swainsonine is an indolizidine alkaloid from the plant Metarrhizium anisopliae that is used as a potent α-mannosidase inhibitor. Product S8195 has been u...


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€313.00 1MG
€384.99 inc. VAT
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Application

Swainsonine is an indolizidine alkaloid from the plant Metarrhizium anisopliae that is used as a potent α-mannosidase inhibitor. Product S8195 has been used in chemical inhibition assays of CHO Lec2 cells to inhibit glycosylation .

Swainsonine is a potent inhibitor of various α-mannosidases, especially of α-mannosidase II. It inhibits glycoprotein processing and also acts as immune modulator.

Biochem/physiol Actions

Swainsonine is a potent α-mannosidase inhibitor. It also has antimetastatic, antiproliferative, and immunomodulatory activity . It also inhibits glycoprotein processing.

Other Notes

Keep container tightly closed in a dry and well-ventilated place.

Packaging

1MG

Preparation Note

Soluble in water, methanol, DMSO

antibiotic activity spectrumneoplastics
assay≥98% (TLC)
biological sourceMetarrhizium anisopliae
colorwhite to faint yellow
formlyophilized powder
InChI keyFXUAIOOAOAVCGD-DCDLSZRSSA-N
InChI1S/C8H15NO3/c10-5-2-1-3-9-4-6(11)8(12)7(5)9/h5-8,10-12H,1-4H2/t5-,6-,7?,8-/m1/s1
mode of actionenzyme | inhibits
Quality Level200
SMILES stringO[C@@H]1CCCN2C[C@@H](O)[C@@H](O)C12
solubilityH2O: soluble 1 mg/mL
storage condition(Keep container tightly closed in a dry and well-ventilated place.)
storage temp.2-8°C
Cas Number72741-87-8
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