Surfactin, from Bacillus subtilis, >=98% (HPLC and TLC)

Code: S3523-10MG D2-231

Application

Surfactin is used as a surfactant to mediate flux of mono-and divalent cations, such as calcium, across lipid bilayer membranes. It is also used to study antitumo...


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€273.00 10MG
€335.79 inc. VAT
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Application

Surfactin is used as a surfactant to mediate flux of mono-and divalent cations, such as calcium, across lipid bilayer membranes. It is also used to study antitumor activity, activity against enveloped viruses, activity against the protoplast of Bacillus megaterium and the activity against Mycoplasma.

Biochem/physiol Actions

Surfactin is a lipopeptide antibiotic that is composed of one β-hydroxy fatty acid, which has a long fatty acid moiety, and seven amino acids. Three of them have D configurations. It is a powerful biosurfactant that causes lysis of erythrocytes and bacteria. It is also a clotting inhibitor. Surfactin is thought to disrupt or disintegrate membranes via physicochemical interaction with the membranes.

General description

Chemical structure: peptide

Other Notes

Keep container tightly closed in a dry and well-ventilated place. Keep in a dry place.

Packaging

10, 50 mg in poly bottle

antibiotic activity spectrumfungi, neoplastics, mycoplasma, Gram-positive bacteria, Gram-negative bacteria, viruses
assay≥98.0% (HPLC)
biological sourceBacillus subtilis
CMC7.5-20 µmol/L (depending on methods)
colorwhite to faint yellow
descriptionzwitterionic
formpowder
InChI keyNJGWOFRZMQRKHT-WGVNQGGSSA-N
InChI1S/C53H93N7O13/c1-30(2)20-18-16-14-13-15-17-19-21-36-28-43(61)54-37(22-23-44(62)63)47(66)55-38(24-31(3)4)48(67)57-40(26-33(7)8)51(70)60-46(35(11)12)52(71)58-41(29-45(64)65)50(69)56-39(25-32(5)6)49(68)59-42(27-34(9)10)53(72)73-36/h30-42,46H,13-29H2,1-12H3,(H,54,61)(H,55,66)(H,56,69)(H,57,67)(H,58,71)(H,59,68)(H,60,70)(H,62,63)(H,64,65)/t36-,37+,38+,39-,40-,41+,42+,46+/m1/s1
mode of actioncell membrane | interferes
Quality Level200
SMILES stringCC(C)CCCCCCCCC[C@@H]1CC(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)O1
solubilityethanol: soluble 10 mg/mL
storage condition(Keep container tightly closed in a dry and well-ventilated place. Keep in a dry place.)
storage temp.2-8°C
Cas Number24730-31-2
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