Palmitic acid, BioXtra, >=99%

Code: P5585-100G D2-231

Application

Palmitic acid has been used:as a medium supplement in chorionic villous tissue culture form placentaas a component of hormone pellet for implantation in mice ovar...


read more

Your Price
€395.00 100G
€485.85 inc. VAT
REQUEST

Application

Palmitic acid has been used:as a medium supplement in chorionic villous tissue culture form placentaas a component of hormone pellet for implantation in mice ovaryfor inducing expression of immunity-related GTPase M (IRGM) in human monocytic cell line, THP-1

Biochem/physiol Actions

Palmitic acid is a straight-chain 16-carbon fatty acid. Diets rich in palmitic acid, along with lauric and myristic acids, are associated with increased serum levels of low-density lipoprotein cholesterol. Palmitic acid is the first fatty acid produced by lipogenesis. It is a negative regulator of acetyl-CoA carboxylase (ACC) and is implicated in fatty acid-induced insulin resistance.

Palmitic acid (PA) is a component of membrane phospholipids (PL) and adipose triacylglycerols (TAG). Elevated levels of palmitic acid contributes to the pathophysiology of atherosclerosis, type 2 diabetes mellitus, neurodegenerative diseases, obesity and cancer. PA promotes apoptosis in the endothelial cell by modulating the p38 mitogen-activated protein kinase (MAPK) pathway and favors expression of TNF-α and reactive oxygen species accumulation. PA promotes interleukin 8 (IL-8) synthesis in hepatocytes contributing to hepatic inflammation. PA by interacting with toll-like receptor 4 (TLR4) induces inflammatory injury in cardiomyoctes.

Packaging

10, 25, 100 g in poly bottle

anion tracessulfate (SO42-): ≤0.05%, chloride (Cl-): ≤0.05%
assay≥99%
biological sourceplant (vegetable)
bp271.5 °C/100 mmHg (lit.)
cation tracesFe: ≤0.0005%, Al: ≤0.005%, Na: ≤0.05%, K: ≤0.005%, Cu: ≤0.0005%, Pb: ≤0.001%, Mg: ≤0.0005%, Zn: ≤0.0005%, NH4+: ≤0.05%, Ca: ≤0.0005%
density0.852 g/mL at 25 °C (lit.)
formpowder
functional groupcarboxylic acid
Gene Informationhuman ... FABP2(2169), FABP3(2170), FABP4(2167), FABP5(2171)
ign. residue≤0.1%
impurities≤0.1% Insoluble matter, ≤0.0005% Phosphorus (P)
InChI keyIPCSVZSSVZVIGE-UHFFFAOYSA-N
InChI1S/C16H32O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16(17)18/h2-15H2,1H3,(H,17,18)
mp61-62.5 °C (lit.)
product lineBioXtra
Quality Level200
shipped inambient
SMILES stringCCCCCCCCCCCCCCCC(O)=O
solubilitychloroform: 0.5 M, clear, colorless
storage temp.room temp
technique(s)cell culture | mammalian: suitable
vapor pressure10 mmHg ( 210 °C)
Cas Number57-10-3
This product has met the following criteria to qualify for the following awards:



PROCEED TO CHECKOUT

HAVE AN ACCOUNT? LOGIN

GUEST CHECKOUT

Proceed as a guest. You will have the option to register to access exclusive pricing and stock availability features after checkout.