3,3-Methylene-bis(4-hydroxycoumarin),

Code: M1390-5G D2-231

Biochem/physiol Actions

Prototype of the 4-hydroxycoumarin class of anticoagulants, which act as vitamin K antagonists, preventing formation of prothrombin. There are many re...


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€47.20 5G
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Biochem/physiol Actions

Prototype of the 4-hydroxycoumarin class of anticoagulants, which act as vitamin K antagonists, preventing formation of prothrombin. There are many reports that dicumarol also inhibits NADPH:quinone oxidoreductase (NQO(1)). In one, it inhibited NQO(1) in a pancreatic cancer cell line, causing increased formation of superoxide and inhibiting cell growth.

Packaging

5, 25 g in poly bottle

assay≥98% (TLC)
biological sourcesynthetic (organic)
formpowder
Gene Informationhuman ... CYP2C9(1559), VKORC1(79001)
InChI keyDOBMPNYZJYQDGZ-UHFFFAOYSA-N
InChI1S/C19H12O6/c20-16-10-5-1-3-7-14(10)24-18(22)12(16)9-13-17(21)11-6-2-4-8-15(11)25-19(13)23/h1-8,20-21H,9H2
mp290-292 °C (lit.)
Quality Level100
SMILES stringOC1=C(CC2=C(O)c3ccccc3OC2=O)C(=O)Oc4ccccc14
solubilitypyridine: 50 mg/mL, clear, faintly yellow to brownish-yellow
Cas Number66-76-2
Hazard Class6.1
Un Number2811
Pack GroupIII
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