Benzo[a]pyrene, >=96% (HPLC)

Code: B1760-100MG D2-231

Application

Benzo[a]pyrene (PAH), a polycyclic aromatic hydrocarbon pollutant, is used as a chemical carcinogen in experimental models of cancer. Carcinogenesis depends on it...


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€73.90 100MG
€90.90 inc. VAT
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Application

Benzo[a]pyrene (PAH), a polycyclic aromatic hydrocarbon pollutant, is used as a chemical carcinogen in experimental models of cancer. Carcinogenesis depends on it′s oxidation by CYP1A1 to benzo[a]pyrenediolepoxide, that forms depurinating adducts with DNA that dissociate to form abasic lesions. Benzo[a]pyrene is a ligand for the arylhydrocarbon receptor (AhR), and some of its biological effects, including the induction of CYP1A1, appear to be mediated via activation of the AhR.

Packaging

100, 250, 500 mg in glass bottle

1, 5 g in glass bottle

assay≥96% (HPLC)
bp495 °C (lit.)
formsolid
InChI keyFMMWHPNWAFZXNH-UHFFFAOYSA-N
InChI1S/C20H12/c1-2-7-17-15(4-1)12-16-9-8-13-5-3-6-14-10-11-18(17)20(16)19(13)14/h1-12H
mp177-180 °C (lit.)
Quality Level200
SMILES stringc1ccc2c(c1)cc3ccc4cccc5ccc2c3c45
Cas Number50-32-8
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