Clarithromycin, >=98% (HPLC)

Code: A3487-100MG D2-231

Application

Clarithromycin has been used to study its effect on the potassium channel KCNJ5WT.

Biochem/physiol Actions

Clarithromycin ...


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€108.00 100MG
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Application

Clarithromycin has been used to study its effect on the potassium channel KCNJ5WT.

Biochem/physiol Actions

Clarithromycin is stable in gastric acid.

Clarithromycin is a macrolide antibiotic that interferes with bacterial protein synthesis. Clarithromycin is an acid-stable version of erythromycin and is particularly effective against Gram-negative bacteria. It has a short half-life, however its metabolite, 14-hydroxy clarithromycin is nearly twice as active as clarithromycin against certain bacteria.

Clarithromycin possess bactericidal activity including anti-mycobacterial activity againstMycobacterium leprae, and M.avium complex.

Other Notes

Keep container tightly closed in a dry and well-ventilated place. Keep in a dry place.

Packaging

100mg

Preparation Note

Practically insoluble in water, soluble in acetone and methylene chloride, slightly soluble in methanol.

antibiotic activity spectrumGram-positive bacteria, Gram-negative bacteria
assay96.0-102.0% (HPLC)
biological sourcesynthetic
colorwhite to off-white
formpowder
InChI keyAGOYDEPGAOXOCK-KCBOHYOISA-N
InChI1S/C38H69NO13/c1-15-26-38(10,45)31(42)21(4)28(40)19(2)17-37(9,47-14)33(52-35-29(41)25(39(11)12)16-20(3)48-35)22(5)30(23(6)34(44)50-26)51-27-18-36(8,46-13)32(43)24(7)49-27/h19-27,29-33,35,41-43,45H,15-18H2,1-14H3/t19-,20-,21+,22+,23-,24+,25+,26-,27+,29-,30+,31-,32+,33-,35+,36-,37-,38-/m1/s1
mode of actionprotein synthesis | interferes
Quality Level200
SMILES stringO[C@@H]([C@@](O)(C)[C@@H](CC)OC([C@H](C)[C@H]1O[C@@H]2O[C@@H](C)[C@H](O)[C@](C)(OC)C2)=O)[C@@H](C)C([C@H](C)C[C@@](C)(OC)[C@H](O[C@@H]3O[C@H](C)C[C@H](N(C)C)[C@H]3O)[C@H]1C)=O
storage temp.2-8°C
Cas Number81103-11-9
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