Trimethoprim, crystallized, >=99.0% (HPLC)

Code: 92131-5G D2-231

Application

Trimethoprim is primarily used as an antibacterial agent. It is used in susceptibility studies of Mycobacterium tuberculosis and mechanism of resistanc...


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€189.00 5G
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Application

Trimethoprim is primarily used as an antibacterial agent. It is used in susceptibility studies of Mycobacterium tuberculosis and mechanism of resistance studies in Haemophilus influenzae .

Primarily used as an antibacterial agent. Dihydrofolate reductase inhibitor with selectivity for the prokaryote enzyme.

Biochem/physiol Actions

Trimethoprim is a dihydrofolate reductase inhibitor with selectivity for the prokaryote enzyme.

Inhibits the synthesis of tetrahydrofolate by procaryote specific dihydrofolate reductase (DHFR).

General description

Chemical structure: pyrimidine

Other Notes

Keep container tightly closed in a dry and well-ventilated place.Light sensitive. Store under inert gas. Moisture sensitive. Product is sensitive to light and moisture.

Packaging

1g,5g,25g

antibiotic activity spectrumGram-positive bacteria, Gram-negative bacteria, mycobacteria
assay≥99.0% (HPLC)
biological sourcesynthetic
colorwhite to yellow
formpowder
Gene Informationhuman ... DHFRP1(573971), KCNH1(3756)rat ... Dhfr(24312)
InChI keyIEDVJHCEMCRBQM-UHFFFAOYSA-N
InChI1S/C14H18N4O3/c1-19-10-5-8(6-11(20-2)12(10)21-3)4-9-7-17-14(16)18-13(9)15/h5-7H,4H2,1-3H3,(H4,15,16,17,18)
mode of actionDNA synthesis | interferes, enzyme | inhibits
mp199-203 °C
Quality Level200
qualitycrystallized
SMILES stringCOc1cc(Cc2cnc(N)nc2N)cc(OC)c1OC
storage temp.2-8°C
Cas Number738-70-5
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