UCL 1684 ditrifluoroacetate hydrate,

Code: U8881-25MG D2-231

Application

UCL 1684 ditrifluoroacetate hydrate has been used for analyzing the mechanism for ammonium-mediated displacement of the protonated analyte from analyte-trifluoroa...


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€1,221.60 25MG
€1,502.57 inc. VAT
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Application

UCL 1684 ditrifluoroacetate hydrate has been used for analyzing the mechanism for ammonium-mediated displacement of the protonated analyte from analyte-trifluoroacetic acid (TFA) ion-pair. UCL 1684 has also been used as a potassium channel inhibitor to study CNP (C-type natriuretic peptide)-induced relaxations in pig coronary arteries.

Biochem/physiol Actions

UCL 1684 is a potent non-peptide blocker of the apamin-sensitive Ca2+-activated K+channel. It comprises two quinolinium rings and is similar to apaminarginine residue. UCL 1684 inhibits calcium-activated K current (Kslow) and modulates islet β-cell.

Features and Benefits

This compound is featured on the Potassium Channels page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Packaging

5, 25 mg in glass bottle

Preparation Note

UCL 1684 ditrifluoroacetate hydrate is soluble in water at 10 mg/ml.

colorwhite to off-white
InChI keyYROHEYZVNZITJN-DDVHGCDCSA-N
InChI1S/C34H28N4.2C3H3F3O2.H2O/c1-3-10-33-29(8-1)31-16-18-37(33)23-27-6-5-7-28(20-27)24-38-19-17-32(30-9-2-4-11-34(30)38)36-22-26-14-12-25(13-15-26)21-35-31;2*4-3(5,6)1-2(7)8;/h1-20H,21-24H2;2*1H2,(H,7,8);1H2/b35-31+,36-32+;;;
Quality Level100
SMILES string[H]O[H].FC(F)(C(O)=O)F.FC(F)(C(O)=O)F.C12=CC=CC=C1C(NCC3=CC=C(CNC4=CC=[N+](C5)C6=C4C=CC=C6)C=C3)=CC=[N+]2CC7=CC=CC5=C7
solubilityDMSO: 10 mg/mL
Cas Number201147-19-5
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