PS372424 hydrochloride; greater than =97% (HPLC)

Code: SML0850-5MG D2-231

Biochem/physiol Actions

PS372424 is a highly specific agonist of human CXCR3 that potently inhibits the migration of activated T cells toward the chemokine mixture in synovia...


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€107.70 5MG
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Biochem/physiol Actions

PS372424 is a highly specific agonist of human CXCR3 that potently inhibits the migration of activated T cells toward the chemokine mixture in synovial fluid from patients with active rheumatoid arthritis. PS372424 activated ERK in T cells with a similar potency and kinetic to the natural ligand CXCL11.

Packaging

5, 25 mg in glass bottle

assay≥97% (HPLC)
colorwhite to beige
formpowder
InChI keyXHGSJQNAEULTAR-DHBRAOIWSA-N
InChI1S/C33H44N6O4.ClH/c34-33(35)36-19-9-16-27(31(42)37-21-23-10-3-1-4-11-23)38-32(43)28-20-25-14-7-8-15-26(25)22-39(28)30(41)18-17-29(40)24-12-5-2-6-13-24;/h2,5-8,12-15,23,27-28H,1,3-4,9-11,16-22H2,(H,37,42)(H,38,43)(H4,34,35,36);1H/t27-,28-;/m0./s1
Quality Level100
SMILES stringO=C(CCC(C1=CC=CC=C1)=O)N2[C@H](C(N[C@@H](CCCNC(N)=N)C(NCC3CCCCC3)=O)=O)CC4=CC=CC=C4C2.Cl
solubilityDMSO: 20 mg/mL, clear
storage temp.2-8°C
Cas Number914291-61-5
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