NNGH, >=98% (HPLC)

Code: SML0584-5MG D2-231

Biochem/physiol Actions

NNGH is a potent and cell-permeable inhibitor of matrix metalloproteinase 3 (MMP-3,stromelysin 1, progelatinase). NNGH has been used to inhibit MMP-3 ...


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€111.90 5MG
€137.64 inc. VAT
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Biochem/physiol Actions

NNGH is a potent and cell-permeable inhibitor of matrix metalloproteinase 3 (MMP-3,stromelysin 1, progelatinase). NNGH has been used to inhibit MMP-3 in a variety of studies. Inhibition of MMP-3 with NNGH significantly suppressed the expression of iNOS and pro-inflammatory cytokines and the activities of NF-KB, AP-1, and MAPK in LPS-stimulated microglia, suggesting a role for MMP-3 in neuroinflammation.

Packaging

5, 25 mg in glass bottle

assay≥98% (HPLC)
colorwhite to beige
formpowder
InChI keyJIRXORZYIXSWOB-UHFFFAOYSA-N
InChI1S/C13H20N2O5S/c1-10(2)8-15(9-13(16)14-17)21(18,19)12-6-4-11(20-3)5-7-12/h4-7,10,17H,8-9H2,1-3H3,(H,14,16)
Quality Level100
SMILES stringCOc1ccc(cc1)S(=O)(=O)N(CC(C)C)CC(=O)NO
solubilityDMSO: 15 mg/mL, clear
storage temp.2-8°C
Cas Number161314-17-6
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