Application
Valspodar/ PSC-833 has been used as a ABCB1 (P-glycoprotein) inhibitor.
Biochem/physiol Actions
Valspodar is a nonimmunosuppressive cyclosporin analog and potent P-glycoprotein (MDR1) inhibitor. Valspodar reverses multidrug resistance (MDR) by inhibiting cellular drug efflux mediated by P-glycoprotein.
Packaging
5, 25 mg in glass bottle
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