Tirapazamine, >=98% (HPLC)

Code: SML0552-10MG D2-231

Application

Tirapazamine has been used to evaluate its cytotoxic effect on U-251 MG (glioblastoma cell line) cell viability.

Biochem/physiol Actions

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€80.30 10MG
€98.77 inc. VAT
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Application

Tirapazamine has been used to evaluate its cytotoxic effect on U-251 MG (glioblastoma cell line) cell viability.

Biochem/physiol Actions

Under hypoxic conditions, tirapazamine is a potent cytotoxic agent that induces apoptosis by inducing breaks in single and double stranded DNA, as well as chromosomal breaks. The compound sensitizes cells to other ionizing radiation and other cytotoxic agents like cisplatin.

Packaging

10, 50 mg in glass bottle

assay≥98% (HPLC)
color, orange to dark orange-red
formpowder
InChI keyORYDPOVDJJZGHQ-UHFFFAOYSA-N
InChI1S/C7H6N4O2/c8-7-9-11(13)6-4-2-1-3-5(6)10(7)12/h1-4H,(H2,8,9)
Quality Level100
shipped inwet ice
SMILES stringNc1n[n+]([O-])c2ccccc2[n+]1[O-]
solubilityDMSO: 10 mg/mL, clear
storage temp.−20°C
Cas Number27314-97-2
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