JTV-519 hemifumarate, >=98% (HPLC)

Code: SML0549-25MG D2-231

Biochem/physiol Actions

JTV-519 is a potent inhibitor or the ryanodine receptor 2 (RYR2) blocker. RYR2 is a cardiac calcium channel that regulates calcium levels in the sarco...


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€494.90 25MG
€608.73 inc. VAT
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Biochem/physiol Actions

JTV-519 is a potent inhibitor or the ryanodine receptor 2 (RYR2) blocker. RYR2 is a cardiac calcium channel that regulates calcium levels in the sarcoplasmic reticulum. JTV-519 stabilizes RYR2 in the closed state.

Features and Benefits

This compound is featured on the InsP3/Ryanodine Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Packaging

5, 25 mg in glass bottle

assay≥98% (HPLC)
colorwhite to beige
formpowder
InChI keyMNAIJOCDPCXVEY-WXXKFALUSA-N
InChI1S/2C25H32N2O2S.C4H4O4/c2*1-29-23-7-8-24-22(18-23)19-27(15-16-30-24)25(28)11-14-26-12-9-21(10-13-26)17-20-5-3-2-4-6-20;5-3(6)1-2-4(7)8/h2*2-8,18,21H,9-17,19H2,1H3;1-2H,(H,5,6)(H,7,8)/b;;2-1+
Quality Level100
SMILES stringOC(=O)C=CC(O)=O.COc1ccc2SCCN(Cc2c1)C(=O)CCN3CCC(CC3)Cc4ccccc4.COc5ccc6SCCN(Cc6c5)C(=O)CCN7CCC(CC7)Cc8ccccc8
solubilityDMSO: 10 mg/mL, clear
storage conditiondesiccated
storage temp.2-8°C
Cas Number145903-06-6
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